Insurance coverage for weight-management medication is inconsistent, and compounded medications are generally not covered at all — so most people pay out of pocket. Here's what GLP-1 options actually cost without insurance, with no games.

Why so many people pay cash

Coverage for GLP-1 medications varies widely by plan and by indication, and prior-authorization rules are strict. Compounded semaglutide and tirzepatide are generally not covered by insurance, so they're almost always a cash purchase. Rather than quote an "after-insurance" price that few people actually get, OS Reboot publishes the real cash price.

What it costs without insurance

No membership fee, 10% off a first order for new patients, and a one-time physician fee on the first order. Compounded options are often the most affordable cash route; they are not FDA-approved and not a copy of an FDA-approved drug.

The honest comparison

Without insurance, compare the total monthly cash cost — the medication plus the visit, with no hidden membership stacked on top. A low sticker price with a monthly membership can quietly cost more over a year than a program with no membership at all.

See the programs and prices → · How GLP-1 pricing works

Educational information, not medical advice, a diagnosis, or a prescription. Pricing is confirmed before anything ships; a licensed physician decides what is appropriate. OS Reboot does not practice medicine or operate a pharmacy.

Frequently asked questions

How much is a GLP-1 without insurance?
Without insurance at OS Reboot, compounded semaglutide starts from about $105 per month and compounded tirzepatide from about $138 per month (physician-evaluated metabolic support); FDA-approved brands for chronic weight management start from $436 per month (Foundayo). No membership fee, and new patients get 10% off a first order.
Does insurance cover compounded semaglutide or tirzepatide?
Compounded medications are generally not covered by insurance, so most people pay out of pocket. OS Reboot publishes a transparent cash price rather than an after-insurance estimate.
What is the lowest-cost GLP-1 without insurance?
At OS Reboot, the lowest-cost cash options are compounded semaglutide (from about $105 per month) and compounded tirzepatide (from about $138 per month), offered for physician-evaluated metabolic support. You are charged only if a licensed physician approves treatment.