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Estriol / Tretinoin Cream at a glance

A prescription cream pairing estriol with tretinoin, a dermatology-grade retinoid — used for skin texture, fine lines and renewal. Usually applied at night. Nothing is prescribed unless a licensed physician determines it is appropriate for you.

Protocol
Estriol / Tretinoin Cream
Category
Skincare
Medicine type
Cream
Availability
Prescription only. A compounded preparation, prepared for an individual patient. Compounded medications are not FDA-approved.
Dispensed by
A U.S. state-licensed 503A compounding pharmacy.

About Estriol / Tretinoin Cream

What it is

A compounded cream combining estriol with tretinoin, a topical retinoid long used in dermatology to speed skin-cell turnover. It is used for texture, fine lines and renewal. Retinoids increase sun sensitivity, so it is usually a nighttime routine.

How it is used

Applied as directed, usually at night, with daily sunscreen as part of the routine.

What to discuss with your physician

Tell your physician if you are pregnant, may become pregnant, or are breastfeeding — retinoids are not used in pregnancy. Also mention hormone-sensitive cancer history and every other topical you apply.

Educational information only. It is not medical advice and does not describe results you should expect. A licensed physician decides what, if anything, is appropriate for you.

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